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How does one approach conducting a design of experiments?

TWI Frequently asked questions

by Marcus Warwick

To assess the impact of critical process control factors on the quality of a finished product, a design of experiments approach is useful. This is not a trivial exercise and is best facilitated by someone experienced in thetechnique. The outcome may be achieved by systematically following a series of steps, as follows:

  1. Define the problem and objectives
  2. Define the process or system
  3. Identify the causal or nuisance factors
  4. Identify the potential control factors
  5. Select levels and ranges for the control factors
  6. Select response variable(s)
  7. Assess measurement gauge capability
  8. Choose experimental design (e.g. sample size, run order)
  9. Collect the experimental material
  10. Perform the experiment
  11. Analyse results to test hypothesis and to develop an empirical model
  12. Predict performance from optimum conditions in empirical model
  13. Run a confirmation trial
  14. Run further experiments at optimum settings

Screening experiments may be used to identify critical factors, with more refined designs then used to identify optimum process conditions.